3-Indolepropionic acid

CAS No. 830-96-6

3-Indolepropionic acid( indole-3-propionic acid | Indolepropionic acid | IPA )

Catalog No. M20040 CAS No. 830-96-6

3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Indolepropionic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.
  • Description
    3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.(In Vitro):3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function.
  • In Vitro
    3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function.
  • In Vivo
    ——
  • Synonyms
    indole-3-propionic acid | Indolepropionic acid | IPA
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    Antioxidant
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer's disease; Friedreich's ataxia

Chemical Information

  • CAS Number
    830-96-6
  • Formula Weight
    189.21
  • Molecular Formula
    C11H11NO2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 50 mg/mL;Water: Slightly Soluble;DMSO: Soluble
  • SMILES
    OC(=O)CCc1c[nH]c2ccccc12
  • Chemical Name
    3-(1H-indol-3-yl)propanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wikoff WR et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3698-703.
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